What is chorionic villus sampling?

Chorionic villus sampling, commonly known as CVS, is a prenatal diagnostic test used to detect genetic disorders and chromosomal abnormalities in a developing fetus. The procedure involves extracting a small sample of placental tissue, either through the cervix (transcervical) or through the abdomen (transabdominal), which is then analyzed in a laboratory.

CVS is typically performed between 10 and 13 weeks of pregnancy, making it an earlier option than amniocentesis for families seeking early genetic screening. The placental tissue contains the same genetic material as the fetus, allowing clinicians to identify conditions such as Down syndrome, cystic fibrosis, sickle cell disease, and other inherited disorders. Results are usually available within one to two weeks.

While CVS offers the advantage of earlier diagnosis, allowing more time for informed decision-making, it carries a slightly higher risk of miscarriage compared to amniocentesis, typically quoted at around 0.2 to 0.5%. Additionally, CVS has a higher rate of inconclusive results that may require follow-up testing. The choice between CVS and amniocentesis depends on individual circumstances, maternal health factors, and the timing preferred by the family. Many high-risk pregnancy specialists in Kuala Lumpur offer both procedures and can advise on which approach suits your situation.